BPC-157 5MG

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The chemicals/materials for sale here are intended for laboratory and research use only, unless otherwise explicitly stated. They are not intended for human ingestion or for use in products that may be ingested.

What Is BPC-157 5MG?

BPC-157 stands for body protection compound 157. It is a synthetic compound composed of 15 amino acids derived from a protein called body protection compound found in human gastric juice. It plays a significant role in preserving the lining of gastric tissues.

Its history dates back to the late 1990s when it was studied by a group of researchers in Croatia. Their initial research was focused on its ability to promote ulcer healing. Later, it gained popularity in the fitness community due to its potential to enhance tissue recovery and performance. It is not approved by the FDA for clinical use. At Pinnacle Peptides, BPC-157 purchase is limited to research purposes only, not for human consumption.

Structure Of BPC-157 5MG

From Pubchem


Synonyms: BPC-15, Booly protection compound 15
Molecular Formula: C62H98N16O22
Molecular Weight: 1419.5 g/mol
CAS number: 137525-51-0
PubChem CID: 108101

Mechanism Of BPC-157 5MG

Its mechanism of action is not clear. However, research shows that it promotes the formation of blood vessels by stimulating vascular endothelial growth factor. Further, it inhibits 4-hydroxynoneal, a molecule produced in the body that negatively impacts cellular growth. Plus, it stimulates the formation of fibroblasts and upregulates the expression of multiple growth receptors.

Pre-Clinical/Clinical Research

1. Wound Healing

Plenty of research on animal models shows that BPC-157 promotes wound healing. One study found that the intraperitoneal delivery of BPC-157 at a dose of 2 micrograms per kilogram enhanced motor function, diminished white and gray matter lesions and alleviated neuronal damage in rats with spinal cord injury [1].

Another study investigated the impact of BPC-157 in rats with acute or chronic gastric ulcers. The results found that BPC-157 dosage through intranasal or intragastric dose reduced ulcer size and enhanced the healing process. Plus, it was also found to promote the rebuilding of glandular epithelium and tissue promotion [2].

Furthermore, BPC-157 has been shown to accelerate wound closure in the alkali-burn rat model. The potential mechanism for this effect includes the deposition of collagen through the ERK1/2 signaling pathway, re-epithelialization and glandular tissue formation [3].

2. Neuroprotection

BPC-157 has been shown to promote neuroprotection. One study found that the intraperitoneal administration of BPC-157 counteracted the effects of MTPT, an agent used to induce damage caused by Parkinson’s disease. It reduced motor abnormalities, decreased hyperactivity and improved somatosensory orientation [4].

Similarly, one study performed on rats has revealed that BPC-157 possesses the ability to mitigate the impacts of cuprizone, a substance known to induce nerve fiber demyelination and damage associated with multiple sclerosis [5]. Furthermore, research shows that BPC-157 can improve memory and locomotion and ameliorate neuronal damage in rats with stroke. These findings suggest that this synthetic peptide might prove to be a useful drug for nervous system disorders [6].

3. Angiogenesis

Numerous studies suggest that BPC-157 promotes angiogenesis, the formation of new blood vessels. In a study, rats with ischemic colitis were administered BPC-157 at a dosage of 10 micrograms per kilogram. The results found that BPC-157 rapidly restored blood supply in the affected region [7].

Another study was conducted on rats in which researchers ligated the inferior vena cava vein to disrupt blood flow, leading to vessel injury and thrombus formation. The results found that BPC-157 treatment caused the redistribution of trapped blood volume and counteracted these effects [8].

The angiogenic effects of BPC-157 may be attributed to the activation of VEGFR2, a cell surface receptor that plays a role in the nitric oxide (NO) signaling pathway. In a study involving rats with hind limb ischemia, BPC-157 treatment was found to increase the expression of VEGFR2, subsequently activating the VEGFR2-Akt-eNOS pathway. Conversely, the administration of dynasore, an inhibitor of VEGFR2, failed to activate the pathway and inhibited endothelial tube formation [9].

4. Recovery of musculoskeletal injuries

Studies on animal models suggest that BPC-157 exhibits the potential to enhance performance and accelerate recovery from injuries. In one study, BPC-157 was administered via intraperitoneal, oral, or topical route following surgical resection in rats. The results indicated improved healing of transected medial collateral ligaments, suggesting that BPC-157 may hold promise for enhancing the recovery of acute ligament injuries [10].

Another study was conducted to suggest the potential mechanism by which BPC-157 enhance the healing process of injured tendons. The findings revealed that BPC-157 accelerated the outgrowth of tendon fibroblasts, enhanced the survival of these cells under H2O2-induced stress, and promoted the migration and spreading of tendon fibroblasts in a dose-dependent manner. Additionally, increased expression of FAk and paxillin was observed, suggesting that these proteins may play a role in mediating the recovery of injured tendons [11].

Furthermore, BPC-157 has shown effectiveness in speeding up the recovery from transected muscle injuries and muscle-crushing injuries in rats. Additionally, it has been shown to mitigate the adverse effects of corticosteroids on tendon-to-bone healing [12].


Studies on animal models suggest that BPC-157 has the potential to accelerate wound healing and recovery of musculoskeletal injuries. It promotes angiogenesis and possesses the ability to offer neuroprotection. However, most of the studies are done on animal models. We need studies on humans to establish its safety and efficacy. As an experimental drug, BPC-157 for sale is only available for research and educational purposes. We don’t support its unwarranted use and encourage you to buy BPC-157 only to support your research.


  1. Perovic, D., et al., Stable gastric pentadecapeptide BPC 157 can improve the healing course of spinal cord injury and lead to functional recovery in rats. Journal of Orthopaedic Surgery and Research, 2019. 14(1): p. 199.
  2. Xue, X.C., et al., Protective effects of pentadecapeptide BPC 157 on gastric ulcer in rats. World J Gastroenterol, 2004. 10(7): p. 1032-6.
  3. Huang, T., et al., Body protective compound-157 enhances alkali-burn wound healing in vivo and promotes proliferation, migration, and angiogenesis in vitro. Drug Des Devel Ther, 2015. 9: p. 2485-99.
  4. Klicek, R., et al., Stable gastric pentadecapeptide BPC 157 heals cysteamine-colitis and colon-colon-anastomosis and counteracts cuprizone brain injuries and motor disability. J Physiol Pharmacol, 2013. 64(5): p. 597-612.
  5. Klicek, R., et al., Stable gastric pentadecapeptide BPC 157 heals cysteamine-colitis and colon-colon-anastomosis and counteracts cuprizone brain injuries and motor disability. J Physiol Pharmacol, 2013. 64(5): p. 597-612.
  6. Vukojevic, J., et al., Pentadecapeptide BPC 157 and the central nervous system. Neural Regen Res, 2022. 17(3): p. 482-487.
  7. Duzel, A., et al., Stable gastric pentadecapeptide BPC 157 in the treatment of colitis and ischemia and reperfusion in rats: New insights. World J Gastroenterol, 2017. 23(48): p. 8465-8488.
  8. Vukojević, J., et al., Rat inferior caval vein (ICV) ligature and particular new insights with the stable gastric pentadecapeptide BPC 157. Vascul Pharmacol, 2018. 106: p. 54-66.
  9. Hsieh, M.-J., et al., Therapeutic potential of pro-angiogenic BPC157 is associated with VEGFR2 activation and up-regulation. Journal of Molecular Medicine, 2017. 95(3): p. 323-333.
  10. Klicek, R., et al., Stable gastric pentadecapeptide BPC 157 heals cysteamine-colitis and colon-colon-anastomosis and counteracts cuprizone brain injuries and motor disability. J Physiol Pharmacol, 2013. 64(5): p. 597-612.
  11. Sikiric, P., et al., A behavioural study of the effect of pentadecapeptide BPC 157 in Parkinson's disease models in mice and gastric lesions induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydrophyridine. J Physiol Paris, 1999. 93(6): p. 505-12.
  12. Vukojevic, J., et al., Pentadecapeptide BPC 157 and the central nervous system. Neural Regen Res, 2022. 17(3): p. 482-487.

Certificate of Analysis (COA)


High Performance Liquid Chromatography (HPLC)


Mass Spectrometry (MS)


What is BPC 157

Body Protective Compound 157, often BPC 157, is a synthetic peptide comprising 15 amino acids. It has drawn interest in scientific studies because of its possible therapeutic effects on numerous physiological systems. BPC 157 is well known for enhancing gastrointestinal health, lowering inflammation, and encouraging tissue regeneration and healing. The effectiveness of it in treating ailments such as muscle rips, tendon damage, and joint problems has been researched.

BPC Peptide Research

While the research on BPC 157 is promising, it is important to note that most studies have been conducted in animal models or in vitro settings. Further clinical trials and human studies are needed to determine the safety, efficacy, and optimal dosing of BPC 157 for various conditions. Here is an overview of the research conducted on BPC 157:

Tissue Healing and Regeneration:

Numerous research has looked into how BPC 157 affects tissue repair and regeneration. Muscles, tendons, ligaments, and bones are just a few of the tissues that it has been shown to help mend. According to research, BPC 157 has been shown to hasten the growth of new blood vessels, improve collagen synthesis, and promote cell proliferation—all of which aid in tissue regeneration and repair.

Anti-Inflammatory Effects:

Strong anti-inflammatory activities are displayed by BPC 157. It has been demonstrated that it does so by preventing the synthesis of pro-inflammatory cytokines and encouraging the generation of anti-inflammatory agents. These illnesses, including arthritis, tendinitis, and inflammatory bowel disease characterized by excessive inflammation, can benefit from BPC 157's anti-inflammatory properties.

Gastrointestinal Health:

Studies have concentrated on the impact of BPC 157 on gastrointestinal health. By aiding in the recovery of gastric ulcers, lowering intestinal inflammation, and reestablishing regular gut motility, it has been shown to play a protective role in the gut. For its possible therapeutic advantages in illnesses like inflammatory bowel disease, colitis, and leaky gut syndrome, BPC 157 has also been researched.

Neuroprotective Properties:

BPC 157 has demonstrated neuroprotective effects in several experimental animals. It has been discovered to support neuronal survival, enhance nerve regeneration, and defend against traumatic or toxic brain injury. These neuroprotective qualities point to possible uses for BPC 157 in treating stroke, traumatic brain injury, and neurodegenerative diseases.

Blood Vessel Formation and Circulation:

Studies have shown that BPC 157 contributes to angiogenesis or the growth of new blood vessels. It has proven to be capable of promoting blood vessel formation and enhancing blood flow, both of which are essential for tissue healing and general health.

Other Potential Benefits:

In addition to the illnesses listed above, BPC 157 has demonstrated promise in several other conditions, including pain relief, organ protection, osteoporosis, and wound healing.

Where to Buy BPC-157

Pinnacle Peptides is one of the best places to buy BPC 157 online for research. When you purchase BPC 157 from us, you can be confident in the quality and purity of our product. We offer a convenient and secure buying experience, ensuring you can easily acquire this remarkable research compound. We also guarantee the highest quality and purity standards. So, unlock the potential of your research with BPC 157 for sale here. Whether you're studying tissue regeneration, injury recovery, or exploring novel therapeutic avenues, this peptide is an indispensable tool.


The products we offer are intended for laboratory research use only. In purchasing any of these items, the customer acknowledges the risks of consuming or distributing these products. These chemicals are NOT intended to use as food additives, drugs, cosmetics, household chemicals, or other inappropriate applications. Listing a material on this site does not constitute a license to its use in infringement of any patent. The products will be handled only by qualified and properly trained professionals. All customers represent and warrant that through their review and study, they are fully aware and knowledgeable about the following: Government regulations regarding the use of and exposure to all products—the health and safety hazards associated with handling the products they purchase. An adequate warning of any products' health and safety hazards is necessary. Pinnacle Peptides reserves the right to limit and deny sales of products to any unqualified individuals if we have reason to believe that misuse will occur.

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DISCLAIMER: The products sold on this site are not a drug nor is it intended to treat, diagnose, cure or prevent any disease, nor is it meant for ANY cosmetic purpose. Pinnacle Peptides makes no claims of alleged beneficial properties of any product on this site if injected or ingested in any manner. Our Peptides are exclusively distributed legally within the laws of safe harbor for research peptides and are to be used for that purpose ONLY. If any country’s governing bodies feel we are in violation of their laws regarding peptides, we ask you contact us immediately via [email protected] so we may expeditiously rectify the situation.All customers represent and warrant that through their own review and study that they are fully aware and knowledgeable about the following:Their government regulations regarding the importation, purchase, possession and use of peptides. The health and safety hazards associated with the handling of peptides in a research setting. That peptides are NOT intended to be used as a food additive, drug, vitamin, supplement, cosmetic or any other inappropriate application. Such a sale would be otherwise denied.
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