GHRP-6 - 5MG

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The chemicals/materials for sale here are intended for laboratory and research use only, unless otherwise explicitly stated. They are not intended for human ingestion or for use in products that may be ingested.

What Is GHRP-6 - 5MG?

GHRP-6, growth hormone-releasing peptide 6, is a synthetic growth hormone secretagogue that has moderate to high selectivity. GHRP-6 has been shown to promote food intake by stimulating hunger and increasing energy metabolism. Research shows that it can positively impact growth hormone deficiency disorders such as obesity. Further, it has been shown to decrease fat, improve memory and exert positive effects on sex motivation and heart muscles. At Pinnacle Peptides, GHRP-6 for sale is exclusively available for research and experimentation.

Structure Of GHRP-6 - 5MG

From Pubchem


Synonyms: GH-Releasing peptide, 87616-84-0
Molecular Formula: C46H56N12O6
Molecular Weight: 873.0 g/mol Sequence: HWAWFK
CAS number: 87616-84-0
PubChem CID: 9919153

Mechanism Of GHRP-6 - 5MG

GHRP-6 is a growth hormone secretagogue/ghrelin receptor agonist. Upon binding to ghrelin receptors, it triggers a series of signalling cascades that eventually lead to the release of growth hormone from the anterior pituitary. Research shows that GH release is mediated by protein kinase C, and it also acts as a functional somatostatin antagonist.

Pre-Clinical/Clinical Research

1. Memory

GHRP-6 has been shown to boost memory and cognitive function. A study conducted on a rat model of Alzheimer’s disease found that GHRP-6 treatment brought improvement in Barnes’s maze task. Furthermore, it restored the levels of leptin, glucose and serum cholesterol along with the reduction in hippocampal amyloid ß and acetylcholinesterase levels [1].

The scientific literature reveals that ghrelin produces its effect on memory by releasing glutamate levels at the presynaptic stage. Glutamate, in turn, binds to the NMDA receptors located on the postsynaptic neuron. Moreover, it enhances the expression of NR2B-subunits, and these effects are thought to be mediated by the activation of the GHS-R1a receptor [2].

2. Stroke

Research shows that GHRP-6 prevent neuronal death following injury. In a study, administration of epidermal growth factor and GHRP-6 improved neuronal survival following ischemic injury. Furthermore, it reduced the infarct size and preserved memory after the attack of stroke as compared to the control group [3].

3. Cardioprotective Effects

Scientific literature points to the fact that GHRP-6 possess cardioprotective effects. A study was conducted to investigate its impact on myocardial infarction size in pigs following coronary artery occlusion. Animals were randomly assigned to receive either GHRP-6 or a normal saline solution. The results revealed a significant reduction in infarct mass (by 78%) and thickness (by 50%). Additionally, a decrease in reactive oxygen species was observed, suggesting that the antioxidant properties of GHRP-6 contributed to mitigating myocardial ischemic damage [4].

In another study, rats with induced heart failure were administered growth hormone-releasing peptides, including GHRP-6, or saline water twice daily for three days. The findings showed that GHRP-6 increased left ventricular ejection fraction and decreased end-diastolic pressure. Moreover, the progression of cardiac cachexia was slowed down, and reduced levels of ANP, renin, and aldosterone were observed [5].

4. Wound Healing

GHRP-6 has been shown to improve wound healing. It reduces scar formation, speeds up wound closure and suppresses inflammation via activation of CD36 receptor [6].

5. Gastric Emptying Time

Ghrelin is a gut hormone that affects gastric emptying time and increases gastric motility. A study was conducted to check the effect of GHRP-6 on diabetic rats with gastroparesis. Gastroparesis is a condition characterized by delayed gastric emptying. The findings indicated that GHRP-6 treatment enhanced gastric emptying time. However, this effect was not observed in the presence of GHRP-6 antagonist [7].

In another study, GHRP-6 and ghrelin were shown to improve gastric emptying time in mice with septic ileus. Research shows that the activation of the cholinergic pathway in the enteric nervous system by ghrelin is responsible for mediating these effects [8].


GHRP-6 is a synthetic agonist of the GHS/ghrelin receptor that stimulates growth hormone release. It has the potential to be used in the treatment of gastroparesis and septic ileus. It also possesses cardioprotective effects and prevents cardiac remodeling following injury. Furthermore, it boosts cognition and accelerates wound healing. We don’t encourage its unwarranted use and offer GHRP-6 purchase exclusively for research. Only buy GHRP-6 if you are an authorized researcher.


  1. Madhavadas, S., B.M. Kutty, and S. Subramanian, Amyloid beta lowering and cognition enhancing effects of ghrelin receptor analog [D-Lys (3)] GHRP-6 in rat model of obesity. Indian J Biochem Biophys, 2014. 51(4): p. 257-62.
  2. Ghersi, M.S., et al., Ghrelin increases memory consolidation through hippocampal mechanisms dependent on glutamate release and NR2B-subunits of the NMDA receptor. Psychopharmacology, 2015. 232(10): p. 1843-1857.
  3. Subirós, N., et al., Assessment of dose–effect and therapeutic time window in preclinical studies of rhEGF and GHRP-6 coadministration for stroke therapy. Neurological Research, 2016. 38(3): p. 187-195.
  4. Berlanga, J., et al., Growth-hormone-releasing peptide 6 (GHRP6) prevents oxidant cytotoxicity and reduces myocardial necrosis in a model of acute myocardial infarction. Clinical Science, 2007. 112(4): p. 241-250.
  5. Xu, X.-B., et al., GH-releasing peptides improve cardiac dysfunction and cachexia and suppress stress-related hormones and cardiomyocyte apoptosis in rats with heart failure. American Journal of Physiology-Heart and Circulatory Physiology, 2005. 289(4): p. H1643-H1651.
  6. Mendoza Marí, Y., et al., Growth Hormone-Releasing Peptide 6 Enhances the Healing Process and Improves the Esthetic Outcome of the Wounds. Plast Surg Int, 2016. 2016: p. 4361702..
  7. Qiu, W.C., et al., Gastric motor effects of ghrelin and growth hormone releasing peptide 6 in diabetic mice with gastroparesis. World J Gastroenterol, 2008. 14(9): p. 1419-24.
  8. De Winter, B.Y., et al., Effect of ghrelin and growth hormone-releasing peptide 6 on septic ileus in mice. Neurogastroenterology & Motility, 2004. 16(4): p. 439-446.

Certificate of Analysis (COA)


High Performance Liquid Chromatography (HPLC)


Mass Spectrometry (MS)


What is GHRP-6?

Growth Hormone Releasing Peptide-6 (GHRP-6) is a man-made peptide of six amino acids. It belongs to the group of substances known as growth hormone secretagogues, which encourage the pituitary gland to secrete growth hormone. When GHRP-6 binds to the ghrelin receptor, a signaling cascade that increases growth hormone release is set off. It is well known for its capacity to increase appetite in addition to its function in promoting growth hormone release. Its potential uses in treating growth hormone insufficiency, promoting muscular growth, and controlling appetite have all been investigated by researchers. The use of GHRP-6 in clinical settings requires proper medical oversight.

GHRP-6 Research

Growth Hormone Releasing Peptide-6 (GHRP-6) is a synthetic peptide that has garnered significant interest in scientific research. Here are the key areas of GHRP-6 research, highlighting its effects and potential benefits.

Stimulation of Growth Hormone Release:

The potential of GHRP-6 to trigger the production of growth hormone (GH) is one of the main areas of interest for this research. The ghrelin receptor, which is present in the hypothalamus and pituitary gland, is what this peptide binds to. A signaling cascade that results from this binding boosts GH secretion. The effectiveness of GHRP-6 in increasing GH release has been thoroughly investigated by researchers in both laboratory settings and clinical trials.

Muscle Growth and Performance Enhancement:

The ability of GHRP-6 to encourage muscle growth and improve athletic performance has been established. Its capacity to promote GH release, which is essential for protein synthesis and muscle repair, contributes to its anabolic effects. According to studies, GHRP-6 supplementation can boost muscle mass, strengthen muscles, and quicken the recovery process after exercise-induced muscle injury. The utility of this peptide in preventing muscle wasting diseases and improving athletic performance has been studied.

Appetite Stimulation and Regulation:

It is well known that GHRP-6 might increase appetite. According to research, GHRP-6 injection increases food intake and increases appetite. When appetite stimulation is sought, like in cases of starvation or the treatment of specific medical problems, this effect may be advantageous. However, the possibility of increased appetite needs to be carefully evaluated because it can have an impact on metabolic health and weight management.

Metabolic Effects and Body Composition:

The metabolic effects of GHRP-6 and prospective impacts on body composition have both been investigated. According to research, GHRP-6 can boost glucose metabolism and lipolysis, the breakdown of fat. Studies on obesity, insulin resistance, and metabolic syndrome are drawn to it because of its beneficial effects on metabolism. Its potential therapeutic uses in altering body weight and metabolic factors are being researched.

Neuroprotective and Cognitive Effects:

Recent studies suggest that GHRP-6 may influence cognitive function and have neuroprotective effects. Its potential for defending neurons, boosting cognitive function, and strengthening memory has been shown in studies. These results have increased interest in researching GHRP-6 as a potential treatment for cognitive decline and neurodegenerative illnesses. To determine the precise mechanisms and therapeutic uses, more study is required.

Where to Buy GHRP-6

If you are looking to purchase GHRP-6 online, then Pinnacle Peptides is the best source. Researching on subjects by researchers with this peptide has now been made easy by Pinnacle Peptides. You can log into our website for availing discounts on this GHRP-6 buy. The GHRP-6 for sale here is intended for laboratory research use only. So, order now and elevate your research for groundbreaking discoveries. However, This product is available here for research purposes only.


In purchasing any item from our website, the customer acknowledges that there are risks involved with consumption or distribution of these products. These chemicals are NOT intended to use as food additives, drugs, cosmetics, household chemicals or other inappropriate applications. The listing of a material on this site does not constitute a license to its use in infringement of any patent. All of the products will be handled only by qualified and properly trained professionals. All customers represent and warrant that through their own review and study that they are fully aware and knowledgeable about the following: Government regulations regarding the use of and exposure to all products. The health and safety hazards associated with the handling of the products they purchase. The necessity of adequately warning of the health and safety hazards associated with any products. Pinnacle Peptides reserves the right to limit and/or deny sales of products to any unqualified individuals if we have reason to believe that misuse will occur.

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DISCLAIMER: The products sold on this site are not a drug nor is it intended to treat, diagnose, cure or prevent any disease, nor is it meant for ANY cosmetic purpose. Pinnacle Peptides makes no claims of alleged beneficial properties of any product on this site if injected or ingested in any manner. Our Peptides are exclusively distributed legally within the laws of safe harbor for research peptides and are to be used for that purpose ONLY. If any country’s governing bodies feel we are in violation of their laws regarding peptides, we ask you contact us immediately via [email protected] so we may expeditiously rectify the situation.All customers represent and warrant that through their own review and study that they are fully aware and knowledgeable about the following:Their government regulations regarding the importation, purchase, possession and use of peptides. The health and safety hazards associated with the handling of peptides in a research setting. That peptides are NOT intended to be used as a food additive, drug, vitamin, supplement, cosmetic or any other inappropriate application. Such a sale would be otherwise denied.
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