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For this product you will need: BACTERIOSTATIC WATER For reconstitution.

The chemicals/materials for sale here are intended for laboratory and research use only, unless otherwise explicitly stated. They are not intended for human ingestion or for use in products that may be ingested.

What Is PAL-GHK 10MG?

Palmitoyl tripeptide, also known as Pal-GHK, is a man-made peptide that is intended to improve skin health, decrease pigmentation, and enhance collagen formation. It consists of a peptide consisting of three amino acids (GHK: glycine, histidine & lysine) and a fatty acid molecule (palmitoyl). It has been found to activate fibroblasts, which are responsible for producing vital proteins in the connective tissues, and skin, bones of the extracellular matrix.

Since 1973, the cosmetics industry has been using Palmitoyl tripeptide, a promising peptide. Research has shown that it enhances the synthesis of collagen and promotes the synthesis of blood vessels. Scientific research is still being conducted to fully comprehend its potential [1]. At Pinnacle Peptides, Pal-GHK for sale is exclusively available for research and experimentation.

Structure Of PAL-GHK 10MG

From Pubchem


IUPAC Name: N-palmitoyl-glycyl-L-histidyl-L-lysine
Synonyms: Palmitoyl Tripeptide-1, Palmitoyl Oligopeptide, Pal-Gly-His-Lys-OH
Molecular Formula: C30H54N6O5
Molecular Weight: 578.8 g/mol
Sequence: GHK
CAS number: 147732-56-7
PubChem CID: 10231864

Mechanism Of PAL-GHK 10MG

Pal-GHK's palmitoyl fatty acid component functions as a carrier, acting as a vehicle for the peptide. This binding of a fatty acid to a peptide sequence enhances its penetration in the skin cells. Essentially, Palmitoyl's role is to facilitate the effective delivery of amino acid tripeptide to the interior of cells deep within the skin, optimizing its utility.

Palmitoyl tripeptide's precise mechanism of action is uncertain. Nevertheless, research shows that it works by inducing the release of two important skin proteins: collagen and decorin [2]. Decorin plays an important role in the regulation of collagen fiber organization and function within the extracellular matrix. Collagen is an important part of the extracellular matrix that provides structural support and keeps the elasticity of the skin.

Pre-Clinical/Clinical Research

1. Wound Healing

Animal studies supported the fact that PAL-GHK has skin healing and regenerating characteristics. An animal trial was conducted on rabbits to study the potential benefits of PAL-GHK. During the trial, the rabbits' skin was intentionally wounded using a laser. Thereafter, PAL-GHK, along with some other drugs, was applied to the wound site on a daily basis for several weeks. The results revealed that PAL-GHK notably accelerated the healing of the wounds as compared to the placebo [3].

2. Aging

In animal trials, Pal-GHK has been reported to protect the skin from different aging-related effects. Pal-GHK exhibits the capability to increase the production of essential proteins like collagen and elastin, important for maintaining skin elasticity and structure. Pal-GHK peptide fragment deceives fibroblasts into assuming that elastin has been damaged. Fibroblasts multiply and develop in response to this deceiving signal, to make up for the loss of elastin in the skin.

The activity of fibroblasts decreases with increasing age. Animal studies suggested that the peptide part of Pal-GHK possesses the ability to regenerate fibroblasts, offering a potential way to counteract some of the common skin-related effects related to the aging process [4].

3. Wrinkles

Pal-GHK has been shown to be effective in hydrating the lips and restoring lips fullness in animal studies [5]. When used in combination with some other short peptides, Pal-GHK produces a synergistic effect, significantly decreasing the appearance of fine lines and wrinkles. Furthermore, research in animal studies suggests that Pal-GHK plays a role in reducing redness and improving skin discoloration caused by sun damage, suggesting its potential to manage different aging-related skin concerns [6].

4. Skin Irritation

An animal study was conducted to assess the effect of Pal-GHK on skin irritation. BIOPEPTIDE CL, which contains 100 ppm of pal-GHK, was studied for skin irritation using three male New Zealand White rabbits [7]. The testing material was applied to both scarified and non-scarified skin on the flank (0.5 ml on a 6 cm2 area, with hair clipped) under an occlusive hypoallergenic dressing for 24 hours. Reactions were assessed at 24 and 72 hours after application. Only a little redness was observed at the 24-hour mark, and no other reactions were listed. BIOPEPTIDE CL was found to be non-irritating, with a PII (Primary Irritation Index) value of 0.3.


Pal-GHK is a man-made peptide known for its skin-benefiting roles. Pal-GHK has the potential to increase the production of collagen and elastin. It has also been found to exhibit the ability to improve skin and cell penetration. It stimulates the growth and multiplication of fibroblasts, making it an important subject for the cosmetics industry. However, further research is needed to authenticate its effects. We don’t support its unwarranted use and offer Pal-GHK purchase solely for research. Only buy Pal-GHK if you are a qualified researcher.

High Performance Liquid Chromatography (HPLC)


Mass Spectrometry (MS)


What is PAL-GHK?

The synthetic peptide PAL-GHK, also called Palmitoyl Tripeptide-1, is made from the amino acids glycine, histidine, and lysine. Due to its possible anti-aging and skin-rejuvenating benefits, it is frequently employed in the skincare industry. In order to promote skin elasticity and firmness, PAL-GHK is thought to increase the synthesis of collagen and other extracellular matrix substances. Additionally, it possesses antioxidant qualities that aid in preventing oxidative stress and damage to the skin. PAL-GHK is frequently included in skincare products to address aging symptoms such fine lines, wrinkles, and sagging skin by boosting skin cell regeneration and enhancing the overall structure of the skin. We use this peptide mainly because it is a good synthesizing agent as well as controller in the production of interleukins.

PAL-GHK Research

The synthetic peptide PAL-GHK, also called Palmitoyl Tripeptide-1, has drawn interest from scientists. The main PAL-GHK research areas are examined here, along with their implications and prospective uses.

Stimulation of Collagen Production:

Collagen Production Stimulation: The capacity of PAL-GHK to promote collagen production is one of the main areas of research. The essential protein collagen gives the skin its structural support and flexibility. According to studies, PAL-GHK can stimulate fibroblasts, which are cells that produce collagen, increasing collagen production. Researchers look at how well PAL-GHK works to increase skin firmness, elasticity, and reduce the visibility of wrinkles and fine lines.

Skin Repair and Regeneration:

Research on PAL-GHK also examines how it can aid in skin regrowth and repair. According to studies, keratinocytes—the cells in charge of skin regeneration—are stimulated to proliferate, which speeds up the healing process. In investigations on wound healing, this peptide has demonstrated promise by encouraging the growth of new blood vessels and the migration of skin cells to the wound site. Researchers are looking into how it might be used to treat burns, scars, and ulcers, among other skin diseases.

Antioxidant Properties:

Antioxidant qualities of PAL-GHK contribute to its potential for skin protection. Skin aging and damage can result from oxidative stress, which is brought on by an imbalance between free radicals and antioxidants in the body. Research on PAL-GHK focuses on its capacity to neutralize free radicals and lessen oxidative stress, shielding the skin from environmental irritants. This antioxidant activity may aid in delaying the onset of aging, enhancing skin texture, and preserving general skin health.

Moisturizing and Hydration:

Research on PAL-GHK's possible moisturizing and hydrating qualities is another area of focus. According to studies, PAL-GHK can improve the skin's capacity to hold onto moisture by encouraging the production of hyaluronic acid, a crucial component in skin hydration. Improved moisture retention may result in skin that is more supple, smoother, and plumper. Researchers look at PAL-GHK's capacity to increase skin moisture levels and its possible application in moisturizing formulations.

Safety and Compatibility:

Research on PAL-GHK additionally focuses on evaluating the peptide's compatibility and safety profile. Researchers assess its potential for skin irritability, cytotoxicity, and interactions with other skincare components. For responsible use in cosmetic formulations and future therapeutic uses, it is crucial to comprehend the safety and compatibility aspects of PAL-GHK.

Where to Buy PAL-GHK(Palmitoyl Tripeptide-1)

If you need this product for your research purpose, you can buy PAL-GHK online at Pinnacle Peptides. They are available in vials of 10Mg at the online store. Purchasing PAL-GHK 10MG as a peptide is now a hassle-free process with Pinnacle Peptides. At resent much research has been going on around this product hence this is much demanded among several scientists all over the world. Pinnacle Peptides can deliver this product to you wherever you are. Whether you are in the United States or at international borders, deliveries are made to your doorstep. However currently products are delivered for only research and/or manufacturing purposes. Direct human intake of this peptide without prescription is prohibited. PAL-GHK for sale here and other peptides which exist naturally are now being synthesized by several cosmetic manufacturing companies. So you should be sure of the product you are purchasing in the market. A proper research work can only be carried out with pure and not synthesized work.


Pinnacle Peptides only produces and sells the purest form of peptides which is why it has been trusted over the years by so many consumers around the world. The products we offer are intended for laboratory research use only. In purchasing any of these items, the customer acknowledges that there are risks involved with consumption or distribution of these products. These chemicals are NOT intended to use as food additives, drugs, cosmetics, household chemicals or other inappropriate applications. The listing of a material on this site does not constitute a license to its use in infringement of any patent. All of the products will be handled only by qualified and properly trained professionals. All customers represent and warrant that through their own review and study that they are fully aware and knowledgeable about the following: Government regulations regarding the use of and exposure to all products. The health and safety hazards associated with the handling of the products they purchase. The necessity of adequately warning of the health and safety hazards associated with any products. Pinnacle Peptides and reserves the right to limit and/or deny sales of products to any unqualified individuals if we have reason to believe that misuse will occur.

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DISCLAIMER: The products sold on this site are not a drug nor is it intended to treat, diagnose, cure or prevent any disease, nor is it meant for ANY cosmetic purpose. Pinnacle Peptides makes no claims of alleged beneficial properties of any product on this site if injected or ingested in any manner. Our Peptides are exclusively distributed legally within the laws of safe harbor for research peptides and are to be used for that purpose ONLY. If any country’s governing bodies feel we are in violation of their laws regarding peptides, we ask you contact us immediately via [email protected] so we may expeditiously rectify the situation.All customers represent and warrant that through their own review and study that they are fully aware and knowledgeable about the following:Their government regulations regarding the importation, purchase, possession and use of peptides. The health and safety hazards associated with the handling of peptides in a research setting. That peptides are NOT intended to be used as a food additive, drug, vitamin, supplement, cosmetic or any other inappropriate application. Such a sale would be otherwise denied.
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