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The chemicals/materials for sale here are intended for laboratory and research use only, unless otherwise explicitly stated. They are not intended for human ingestion or for use in products that may be ingested.


PT-141, also known as bremelanotide, is a synthetic derivative of alpha-melanocyte-stimulating hormone. It is an FDA-approved drug for hypoactive sexual desire disorder treatment in postmenopausal women. Researchers are interested in investigating its effect on male sexual health and weight loss. At Pinnacle Peptides, PT-141 for sale is exclusively available for research purposes, not for human consumption.

Structure Of PT-141 (BREMELANOTIDE) 10MG

From Pubchem


Synonyms: Bremelanotide, PT-141
Molecular Formula: C50H68N14O10
Molecular Weight: 1025.2 g/mol
CAS number: 189691-06-3
PubChem CID: 9941379


In pursuit of a treatment for sexual dysfunction, Competitive Technologies licensed Melanotan II to Palatin Technologies. However, Palatin ceased the development of melanotan-II in 2000 and began working on bremelanotide, a derivative of melanotan-II with distinct chemical properties. Competitive Technologies sued Palatin for breach of contract and ownership claims regarding bremelanotide. The parties settled in 2008, with Palatin retaining rights to bremelanotide and returning MT-II rights to the other company. FDA accepted Bremelanotide's New Drug Application for female sexual dysfunction in June 2018 and approved the drug for clinical use in the United States in June 2019.

Mechanism Of PT-141 (BREMELANOTIDE) 10MG

PT-141 acts as a non-selective agonist of melanocortin receptors: MC1R, MC3R, MC4R and MC5R. MC4R is involved in various physiological functions, including sexual arousal and desire. When PT-141 activates MC4R, it triggers the cascade of neural and hormonal responses involved in sexual response. Further, it is believed that MC3R activation might also contribute to the drug’s response.

Pre-Clinical/Clinical Research

1. Weight Loss

Research shows that melanocortin receptors are involved in appetite regulation. Findings from two phase one trials provide evidence of bremelanotide's potential for weight loss. In the first study, postmenopausal women receiving Pt-141 experienced significant weight loss and an average decrease in daily caloric consumption (400 kcal/day) compared to the control group. The second study found similar outcomes, indicating that women who received PT-141 twice daily lost weight and reduced calorie intake [1].

2. Sexual Health

Research shows that MC4R activation improves sexual response. One study found that 10 mg bremelanotide administered 45 minutes prior to intercourse improved sexual response in men who previously didn’t respond to sildenafil [2]. Another study assessed the safety and effect of coadministration of sildenafil and PT-141 in men with erectile dysfunction. The response was greater in patients who received the combination therapy as compared to those who only took sildenafil. Further, the administration of PT-141 along with sildenafil was well-tolerated, suggesting that the combination might be effective in patients who don’t respond to monotherapy [3].

In a phase I clinical trial, the safety, tolerance, and pharmacokinetic effects of bremelanotide were assessed in both male and female participants. The participants were randomly assigned to receive either a 20mg dose of PT-141 via the nasal route or a placebo, with or without ethanol. The study results indicated that a 20 mg intranasal dose of BMT is safe and generally well-tolerated in women, with average peak ethanol concentrations exceeding 80 mg/dL [4].

Another phase II trial found that self-administered subcutaneous PT-141 was effective and safe for premenopausal women with sexual dysfunction [5]. FDA approved the use of PT-141 for hypoactive sexual desire disorder in postmenopausal women based on two phase 3 clinical trials. These studies demonstrated the efficacy and safety of 0.75mg bremelanotide administered subcutaneously in women with hypoactive sexual desire disorder. The results showed that women who took PT-141 experienced a reduction in sexual distress and an increase in desire compared to those who received a placebo. Common side effects associated with bremelanotide included nausea, vomiting, and flushing [6].


PT-141 is a synthetic peptide analog of alpha-melanocyte stimulating hormone. It binds to MC4R receptors in the hypothalamus and improves the sexual response. It is approved for the treatment of hypoactive sexual desire disorder in postmenopausal women. Furthermore, it has the potential to treat male sexual dysfunction. We don’t encourage its unwarranted use and offer PT-141 purchase for research only. Buy PT-141 from Pinnacle Peptides to elevate your research.

Certificate of Analysis (COA)


High Performance Liquid Chromatography (HPLC)


Mass Spectrometry (MS)


What is PT-141?

PT-141 (Bremelanotide) 10MG, also called the libido drug, is quite popular among researchers and scientists alike. Studies have shown that this peptide is essentially beneficial in restructuring the libidinous system. Also known as Bremelanotide it has been under experimentation for various studies. Scientists have claimed that they produce results when subjected to erectile dysfunction in mammalians. They have also been seen to be useful in female arousal dysfunction, vaginal artery smoothness and disorders related to vaginal walls. However they may or may not be limited to such areas itself which is why further studies have been going on related to this peptide.

PT-141 Research

Synthetic peptide PT-141, also referred to as Bremelanotide, has received a lot of attention in the fields of sexual health and medicine. In order to give a comprehensive summary of the research on PT-141, Here we will concentrate on the drug's mechanism of action, prospective therapeutic uses, and related clinical trials.

Mechanism of Action

The MC4 receptor subtype is the one that PT-141 specifically targets as an agonist of the melanocortin receptors. MC4 receptor stimulation in the central nervous system is how PT-141 increases arousal and sexual desire. The circuits involved in sexual behavior are thought to be modulated, and the release of neurochemicals linked to arousal is thought to be encouraged.

Potential Therapeutic Applications

Treatment of Erectile Dysfunction (ED):

PT-141 has demonstrated encouraging results as a potential ED treatment. Its capacity to cause penile erection in ED-afflicted males, even those who are resistant to phosphodiesterase type 5 (PDE5) inhibitors like Viagra, has been shown in clinical research. People who don't respond well to typical ED drugs have a different therapy option thanks to PT-141's method of action, which avoids the nitric oxide route.

Female Sexual Arousal Disorder (FSAD):

Female Sexual Arousal Disorder (FSAD): PT-141 has also been researched for its potential to treat FSAD, a disorder marked by ongoing or recurring problems eliciting sexual arousal. Clinical studies have revealed that giving women PT-141 boosts their subjective sexual arousal and desire, pointing to the drug's potential as a cutting-edge treatment for FSAD.

Clinical Trials

A number of clinical trials have been carried out to evaluate the effectiveness and safety of PT-141 in different patient populations:

Phase II Trials:

When compared to a placebo, PT-141 significantly improved erectile function in a phase II trial including males with ED. Similar encouraging outcomes were seen in a phase IIb trial with FSAD-afflicted women.

Phase III Trials:

Phase III trials for ED and FSAD have been advanced for PT-141. If these trials are successful, PT-141 might be given regulatory approval for these uses. Their goal is to further assess its efficacy and safety characteristics.

Where to Buy PT-141

At Pinnacle Peptides you will find PT-141 for sale in vials of 10MG simply for research purposes and not for average human intake. Buy PT-141 10MG in its purest form from Pinnacle Peptides and be ensured of a high rate of success in all your experiments. We offer you the best range of these peptides. The quality of the products is credible and trusted by many scientists all over the world. You can buy PT-141 online in single vials or order them in bulk as per your research requirements. They are easily availed while all you have to do is just select and order online, and have them delivered at your doorstep .If you are a non resident of USA, you do not have to worry, because even then you can have them delivered at your place, since international deliveries are made as well. If you want to purchase this item for your research, you might as well get in touch with the online source and avail them for research and/or medicinal uses.


The products we offer are intended for laboratory research use only. In purchasing any of these items, the customer acknowledges that there are risks involved with consumption or distribution of these products. These chemicals are NOT intended to use as food additives, drugs, cosmetics, household chemicals or other inappropriate applications. The listing of a material on this site does not constitute a license to its use in infringement of any patent. All of the products will be handled only by qualified and properly trained professionals. All customers represent and warrant that through their own review and study that they are fully aware and knowledgeable about the following: Government regulations regarding the use of and exposure to all products. The health and safety hazards associated with the handling of the products they purchase. The necessity of adequately warning of the health and safety hazards associated with any products. Pinnacle Peptides and reserves the right to limit and/or deny sales of products to any unqualified individuals if we have reason to believe that misuse will occur.

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