99 % of 100
In stock
399.9 Reward Points will be used to purchase this product

Buy this product and Earn 20.00 Pinnacle Points click here to login



For this product you will need: BACTERIOSTATIC WATER For reconstitution.

The chemicals/materials for sale here are intended for laboratory and research use only, unless otherwise explicitly stated. They are not intended for human ingestion or for use in products that may be ingested.


Selank is a synthetic heptapeptide that is made up of seven amino acids. It comprises two parts, one is a tripeptide chain (Pro-Gly-Pro) and the other is a short fragment from immunoglobulin (IgG). It is an analog of tuftsin, a naturally occurring tetrapeptide involved in regulating the immune system. Research suggests it might improve memory, alleviate anxiety, reduce pain and boost the body’s natural defense system. It has not been approved by the FDA yet. At Pinnacle Peptides, selank for sale is exclusively available for research and educational institutions.

Structure Of SELANK 5MG

From Pubchem


IUPAC Name: (2S)-1-[2-[[(2S)-1-[(2S)-2-[[(2S)-1-[(2S)-6-amino-2-[[(2S,3R)-2-amino-3-hydroxybutanoyl]amino]hexanoyl]pyrrolidine-2-carbonyl]amino]-5-(diaminomethylideneamino)pentanoyl]pyrrolidine-2-carbonyl]amino]acetyl]pyrrolidine-2-carboxylic acid
Synonyms: 129954-34-3, Selanc and TP-7
Molecular Formula: C33H57N11O9
Molecular Weight: 751.9 g/mol
Sequence: TK PRPGP
CAS number: 129954-34-3
PubChem CID: 11765600

Mechanism Of SELANK 5MG

Selank has been found to mimic the action of benzodiazepines that bind with GABA receptors. One study shows that selank modulates at least 84 genes that are somehow related to the expression of GABA receptors. This results in the increased affinity of these receptors to the GABA neurotransmitter.

Plus, the binding of selank with GABA receptors enhances its inhibitory action without causing side effects associated with benzodiazepines [1]. This, in turn, can result in anxiolytic effects and enhanced cognition. Furthermore, it has also been shown to interact with the immune system and modulate cytokine production.

Pre-Clinical/Clinical Research

1. Neuroprotection

Literature suggests that selank exhibits neuroprotective effects by enhancing neuronal survival and promoting regeneration. Uncontrolled inflammation and oxidative stress can damage body cells, including neurons. Selank has anti-oxidant and anti-inflammatory properties, and it has been shown to reduce the level of reactive oxygen species in the body [2].

Furthermore, one study was conducted to check the effect of tuftsin analog on memory impairment and the content of brain-derived neurotrophic factor. The rats received 10% ethanol as the only fluid source for 30 days. The results found that selank prevented ethanol-induced memory and attention-related disturbances. Furthermore, it also stopped the increase in brain-derived neurotrophic factors in the hippocampal and frontal cortex [3].

2. Cognition

Different studies in animal models confirm the cognition-enhancing effects of selank. In one study, researchers trained Wister rats with a food reward with 30 trials per day. By the 10th trial, subjects were randomized to receive selank or saline solution. Investigators found that a single dose of selank activated the 5-HT metabolism and the caudal part of the brain stem. Furthermore, it was revealed that this synthetic peptide can stimulate an increase in memory trace stability for 30 days [4].

Similarly, another study was conducted to find out the effect of selank in rats with poor learning ability. The experiment was based on the acquisition of a conditioned active avoidance reflex, a type of learned behavior in which the subject tries to avoid the stimulus that causes unwanted consequences. Rats were randomized to receive selank and the other peptide drug 15 minutes before the training session for four days. The researchers found that selank improved the learning process in rats with poor cognition, and this effect was apparent even after the first dose on day 1. The maximum optimal activity of the selank was seen for the 3rd day [5].

3. Pain Management

Research shows that selank helps prevent the breakdown of molecules called enkephalin. These are molecules present in the body that bind to opioid receptors and lessen the intensity of pain. Moreover, these molecules are thought to be involved in the regulation of other bodily functions, such as stress management, concentration and memory [6].

4. Anxiolytic Effects

Research suggests that selank might have the potential to act as an anxiolytic agent. One study was conducted to check the effect of selank on patients with generalized anxiety and neurasthenia. Thirty patients received selank and 32 subjects took medazepam. Following the study, researchers analyzed participants' states with psychometric scales. The findings indicated that both drugs had anxiolytic effects but the selank also acted as a neurasthenic and psychostimulant agent [7].

Furthermore, selank has been shown to suppress IL-6 production in patients with depression. However, this effect was not observed in healthy individuals. This suggests that selank can be used to treat people with anxiety-asthenic disorders [8].

5. Stress Management

Selank has also been shown to regulate the neurotransmitters responsible for the body’s stress response. A study was conducted to assess the effect of selank on rats treated with serotonin inhibitors. The results found that the peptide drug boosted the selank metabolism in the brain stem right after the injection. These findings suggest that selank can be used to treat stress disorders related to serotonin disturbance [9].


Selank is a synthetic analog of tuftsin that is involved in regulating the body’s immune system. It mimics the action of benzodiazepines and mediates its effect through GABA receptors. It has been to shown alleviate anxiety, decrease stress, enhance cognition and boost neuroprotection. It has not been approved by the FDA yet and requires further research. We don’t support its unwarranted use and offer selank purchase exclusively for research. Only buy selank if you are an authorized researcher.


  1. Volkova, A., et al., Selank Administration Affects the Expression of Some Genes Involved in GABAergic Neurotransmission. Frontiers in Pharmacology, 2016. 7.
  2. Fomenko, E.V., et al., Effect of Selank on Functional State of Rat Hepatocytes under Conditions of Restraint Stress. Bull Exp Biol Med, 2017. 163(4): p. 415-418.
  3. Kolik, L.G., et al., Selank, Peptide Analogue of Tuftsin, Protects Against Ethanol-Induced Memory Impairment by Regulating of BDNF Content in the Hippocampus and Prefrontal Cortex in Rats. Bull Exp Biol Med, 2019. 167(5): p. 641-644.
  4. Semenova, T.P., Kozlovskiĭ, II, N.M. Zakharova, and M.M. Kozlovskaia, [Experimental optimization of learning and memory processes by selank]. Eksp Klin Farmakol, 2010. 73(8): p. 2-5.
  5. Kozlovskii, II and N.D. Danchev, The optimizing action of the synthetic peptide Selank on a conditioned active avoidance reflex in rats. Neurosci Behav Physiol, 2003. 33(7): p. 639-43.
  6. Kost, N.V., et al., Semax and Selank Inhibit the Enkephalin-Degrading Enzymes of Human Serum. Russian Journal of Bioorganic Chemistry, 2001. 27(3): p. 156-159..
  7. Zozulia, A.A., et al., [Efficacy and possible mechanisms of action of a new peptide anxiolytic selank in the therapy of generalized anxiety disorders and neurasthenia]. Zh Nevrol Psikhiatr Im S S Korsakova, 2008. 108(4): p. 38-48.
  8. Uchakina, O.N., et al., [Immunomodulatory effects of selank in patients with anxiety-asthenic disorders]. Zh Nevrol Psikhiatr Im S S Korsakova, 2008. 108(5): p. 71-5.
  9. Semenova, T.P., kozlovskiĭ, II, N.M. Zakharova, and M.M. Kozlovskaia, [Comparison of the effects of selank and tuftsin on the metabolism of serotonin in the brain of rats pretreated with PCPA]. Eksp Klin Farmakol, 2009. 72(4): p. 6-8.

Certificate of Analysis (COA)


High Performance Liquid Chromatography (HPLC)


Mass Spectrometry (MS)


What is Selank?

Selank, a synthetic peptide, has drawn interest because of its potential medicinal benefits for treating anxiety and brain function. Selank, a modified form of the peptide tuftsin that occurs naturally, was created in Russia. It is well known for having anxiolytic qualities, which means that it might lessen anxiety and encourage serenity. Selank has also being investigated for its possible nootropic benefits, which could improve cognitive skills like learning, memory, and focus. Selank has potential as a novel molecule in the area of mental health and cognitive enhancement, even if more research is required to fully understand its mechanisms of action and clinical applications.

Selank Research

Due to its potential therapeutic benefits on anxiety and cognitive function, selank, a synthetic peptide produced from tuftsin, has attracted extensive attention. The study on Selank is summarized here with an emphasis on its mechanisms of action, possible therapeutic uses, and related clinical investigations.

Mechanisms of Action

The mechanisms of action of selank are intricate and still poorly understood. However, multiple mechanisms are thought to be involved in how it works:

Regulation of Neurotransmitters:

Gamma-aminobutyric acid (GABA), dopamine, and serotonin are just a few of the neurotransmitters that selank may affect in the brain's levels. Selank has been demonstrated to have anxiolytic and mood-regulating effects via affecting the balance of these neurotransmitters.

BDNF Stimulation:

Selank has been proven to increase the expression of brain-derived neurotrophic factor (BDNF), which is stimulated. BDNF is an essential factor in increasing synaptic plasticity, which is essential for learning and memory, as well as the growth and survival of neurons.

Potential Therapeutic Applications

Anxiety Disorders:

Generalized anxiety disorder (GAD), social anxiety disorder (SAD), and post-traumatic stress disorder (PTSD) are among the several anxiety disorders for which selank has showed promise as a prospective treatment. Clinical investigations have shown that it has anxiolytic effects and can lessen symptoms of anxiety in people with these diseases.

Cognitive Enhancement:

Selank's putative nootropic benefits on cognitive enhancement have also received attention. Selank may enhance cognitive performance, including memory, attention, and executive functioning, according to research. It might improve cognitive resilience to stress and learning capacities.

Clinical Studies

Animal Studies:

Research on animals has shed important light on the effects of selank. These research have shown how effective it is at reducing anxiety-related behaviors in rodents, among other things. Additionally, they have demonstrated gains in memory and concentration skills.

Human Trials:

Clinical trials on humans have looked into the medicinal potential of selank. Its effectiveness and safety have been examined in these investigations in patients with anxiety disorders and cognitive impairment. Although early results are promising, more investigation is required to determine the ideal dosage, long-term effects, and potential drug interactions.

Where to Buy Selank

Pinnacle Peptides avails SELANK 5MG for research oriented purposes. You can buy Selank online in vials of 5MG and order bulk items as well. SELANK for Sale available at our online store is strictly for research purposes only. They can be harmful when ingested directly. We understand your need to have the peptides in their pure form. Hence these peptides are provided in a non-diluted and in their purest form so that you can achieve the desired results in your experiments. Beware of purchasing Selank from a non trusted site. You might just end up with little or no results.


The products we offer are intended for laboratory research use only. In purchasing any of these items, the customer acknowledges that there are risks involved with consumption or distribution of these products. These chemicals are NOT intended to use as food additives, drugs, cosmetics, household chemicals or other inappropriate applications. The listing of a material on this site does not constitute a license to its use in infringement of any patent. All of the products will be handled only by qualified and properly trained professionals. All customers represent and warrant that through their own review and study that they are fully aware and knowledgeable about the following: Government regulations regarding the use of and exposure to all products. The health and safety hazards associated with the handling of the products they purchase. The necessity of adequately warning of the health and safety hazards associated with any products. Pinnacle Peptides reserves the right to limit and/or deny sales of products to any unqualified individuals if we have reason to believe that misuse will occur.

Submit your review to Earn 50 Pinnacle Points click here to login

Write Your Own Review
You're reviewing:SELANK 5MG
Your Rating
DISCLAIMER: The products sold on this site are not a drug nor is it intended to treat, diagnose, cure or prevent any disease, nor is it meant for ANY cosmetic purpose. Pinnacle Peptides makes no claims of alleged beneficial properties of any product on this site if injected or ingested in any manner. Our Peptides are exclusively distributed legally within the laws of safe harbor for research peptides and are to be used for that purpose ONLY. If any country’s governing bodies feel we are in violation of their laws regarding peptides, we ask you contact us immediately via [email protected] so we may expeditiously rectify the situation.All customers represent and warrant that through their own review and study that they are fully aware and knowledgeable about the following:Their government regulations regarding the importation, purchase, possession and use of peptides. The health and safety hazards associated with the handling of peptides in a research setting. That peptides are NOT intended to be used as a food additive, drug, vitamin, supplement, cosmetic or any other inappropriate application. Such a sale would be otherwise denied.
Product List

Research Peptides

Research Chems

GLP-1 Peptides