What Is PALMITOYL-PENTA 10MG?
Palmitoyl pentapeptide (Pal-KTTKS), consists of five amino acids bound to a 16-carbon aliphatic chain. The palmitoyl acid is attached to enhance the peptide penetration through the lipid barriers of the skin. This man made peptide has been shown to treat wrinkles and improve signs of aging, providing a replacement to commonly used skincare ingredients such as retinol and vitamin C. It promises potential benefits for skin health, but further research is needed to authenticate its effect. At Pinnacle Peptides, Palmitoyl pentapeptide for sale is exclusively available for research and experimentation.
Structure Of PALMITOYL-PENTA 10MG
IUPAC Name: N-palmitoyl-L-lysyl-L-threonyl-L-threonyl-L-lysyl-L-serine
Synonyms: Matrixyl, PALMITOYL PENTAPEPTIDE, Palmitoyl pentapeptide-3, Palmitoyl pentapeptide-4
Molecular Formula: C39H75N7O10
Molecular Weight: 802.1 g/mol
CAS number: 214047-00-4
PubChem CID: 9897237
Mechanism Of PALMITOYL-PENTA 10MG
Palmitoyl pentapeptide is a very precise and biologically active peptide. It is structurally similar to the precursor molecule of collagen Type I. It has been found to stimulate the production of important components like elastin, fibronectin, glucosaminoglycan, and different collagens types (specifically I, III, and IV), supporting the extracellular matrix and wound healing.
Palmitoyl pentapeptide provides an anti-wrinkle effect, by activating the neo-synthesis of macromolecules of extracellular matrix. Moreover, it helps in repairing the matrix and epidermal-dermal junction, enhancing the gene expression for wound healing.
Palmitoyl pentapeptide holds the potential to increase the dermal matrix production in fibroblasts. Research reveals that skin wrinkling is related with damage to dermal matrix components like collagen. The drugs that increase the production of collagen may also reduce wrinkle appearance. A 12 week double-blind randomized clinical trial was conducted to assess the effectiveness of a moisturizer containing 3 ppm of Palmitoyl pentapeptide (pal-KTTKS). The result suggested that Pal-KTTKS is well-tolerated. Moreover, it significantly reduced wrinkles and fine lines compared to the other group .
Similarly, another trial assessed the effectiveness of a 7% Palmitoyl Pentapeptide-4 serum in reducing wrinkles around the eyes. Fifteen women aged between 35 to 65 with wrinkles around their eyes were made to apply the serum twice daily for 8 weeks. Results showed that the 7% Palmitoyl Pentapeptide-4 serum was safe and effective as it reduced wrinkle appearance and improved skin elasticity around the eyes .
Crow's feet are a prominent sign of aging. A double-blind randomized trial, involving 21 Indonesian females aged between 26 to 55, was conducted to assess the effect of Pal-KTTKS on cow’s feet. Over eight weeks of trial, participants received either AHP-3 cream or Palmitoyl pentapeptide-4 cream. The products were applied twice daily to the area around the eyes. Analysis of clinical photos and data revealed significant improvements in subjects using both AHP-3 and Palmitoyl pentapeptide-4. Interestingly, Palmitoyl pentapeptide-4 gave better results compared to AHP-3, supported by data, clinical photos, and self-assessment . These trial results suggested the potential effectiveness of Palmitoyl pentapeptide-4 in addressing signs of aging.
3. Wound Healing
Palmitoyl pentapeptide has been found to improve the wound healing process by promoting the production of important components such as collagen and fibronectin. Its application stimulates the repair of the extracellular matrix, contributing to enhanced skin regeneration and overall wound healing. A study reported that 0.1 µM palmitoyl pentapeptide inhibited the expression of α-SMA (a marker of fibroblasts responsible for collagen production) and reduced the transformation of fibroblasts into myofibroblasts. The extent of this reduction depends on the dose. However, a higher concentration of 0.5 µM was associated with the increased expression of the pro-fibrotic mediator α-SMA. The effective use of palmitoyl pentapeptide for wound healing requires a careful balance between its beneficial wound-healing properties and its potential to promote fibrosis, emphasizing the importance of selecting an appropriate therapeutic dose .
Palmitoyl pentapeptide has been shown to prevent wrinkles, facilitate wound healing and repair skin, Furthermore, it addresses concerns around the eye contour and caters to the specific needs of mature skin. However, more research is needed to validate its therapeutic potential. We don’t support its unwarranted use and offer palmitoyl pentapeptide purchase solely for research. Only buy palmitoyl pentapeptide if you are a qualified researcher.
- Jones, R.R., et al., Collagen stimulating effect of peptide amphiphile C16–KTTKS on human fibroblasts. Molecular pharmaceutics, 2013. 10(3): p. 1063-1069.
- Robinson, L., et al., Topical palmitoyl pentapeptide provides improvement in photoaged human facial skin 1. International journal of cosmetic science, 2005. 27(3): p. 155-160.
- Suhendra, N.N. The efficacy of 7% palmitoyl pentapeptide-4 serum for the periorbital wrinkle reduction. in Rangsit Graduate Research Conference: RGRC. 2020.
- Aruan, R.R., et al., Double-blind, Randomized Trial on the Effectiveness of Acetylhexapeptide-3 Cream and Palmitoyl Pentapeptide-4 Cream for Crow's Feet. The Journal of Clinical and Aesthetic Dermatology, 2023. 16(2): p. 37.
- Park, H., E. An, and A.-R. Cho Lee, Effect of palmitoyl-pentapeptide (Pal-KTTKS) on wound contractile process in relation with connective tissue growth factor and α-smooth muscle actin expression. Tissue engineering and regenerative medicine, 2017. 14: p. 73-80.
PALMITOYL PENTA 10MG is basically a peptide that finds its usage mostly in skin care products. The benefits of this product are that it prevents the skin from aging. It is an essential ingredient in many commercial skin care elements. Chemically speaking, this compound is pretty small in molecular structure. It is made up of 5 amino acids that are linked together and stuck to a fatty acid. You will get this product at Pinnacle Peptides at a very low price. Pinnacle Peptides prides at providing products at the most unbeatable prices however there are no compromises on the quality of the products. All the products are available in the most pure form. With these peptides you can achieve the best results at your experiments. This is why Pinnacle Peptides has been recognised by so many researchers worldwide. So you can purchase your items in bulk or you can at first try out these products and check out the quality. How this peptide is helpful and how you can avail it in the easiest way from your trusted supplier Pinnacle Peptides PALMITOYL PENTA 10MG when added to the key skin cells, the fibroblasts, stimulate the synthesis of the skin elements, the elastin, the collagen and the glucosamnoglycans. However sometimes the results produced under controlled environment in the test tubes do not produce the same results as they do in the flesh and blood. The peptide has so far been effectively beneficial during observation, but whether or not it can yet be claimed as a miraculous drug for anti wrinkle treatment remains debatable. Further research is essential in this field to ensure good results. This is why this peptide is in so much demand nowadays among the scientist folks. Well, if you require this product to carry out your tests, you will get the purest of them at the online store. You will find all peptides and chemicals here as per your requirement. At present PALMITOYL PENTA 10MG is being sold in vials of 10MG. You can purchase these peptides in bulk quantities from the online stores at the best prices. The products we offer are intended for laboratory research use only. In purchasing any of these items, the customer acknowledges that there are risks involved with consumption or distribution of these products. These chemicals are NOT intended to use as food additives, drugs, cosmetics, household chemicals or other inappropriate applications. The listing of a material on this site does not constitute a license to its use in infringement of any patent. All of the products will be handled only by qualified and properly trained professionals. All customers represent and warrant that through their own review and study that they are fully aware and knowledgeable about the following: Government regulations regarding the use of and exposure to all products. The health and safety hazards associated with the handling of the products they purchase. The necessity of adequately warning of the health and safety hazards associated with any products. Pinnacle Peptides and pinnaclepeptides.com reserves the right to limit and/or deny sales of products to any unqualified individuals if we have reason to believe that misuse will occur.